Circulating Metabolites and Cardiovascular Disease in Asians with Chronic Kidney Disease.

ABSTRACT:

Introduction

Chronic kidney disease (CKD) is a growing public health problem, with significant burden of cardiovascular disease and mortality. The risk of cardiovascular disease in CKD is elevated beyond that predicted by traditional cardiovascular risk factors, suggesting that other factors may account for this increased risk. Through metabolic profiling, this study aimed to investigate the associations between serum metabolites and prevalent cardiovascular disease in Asian patients with CKD to provide insights into the complex interactions between metabolism, cardiovascular disease and CKD.

Methods

This was a single-center cross-sectional study of 1,122 individuals from three ethnic cohorts in the population-based Singapore Epidemiology of Eye Disease (SEED) study (153 Chi

SUBMITTER: Cai J 

PROVIDER: S-EPMC10664326 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature