Genome-wide identification and characteristic analysis of ETS gene family in blood clam Tegillarca granosa.

ABSTRACT:

Background

ETS transcription factors, known as the E26 transformation-specific factors, assume a critical role in the regulation of various vital biological processes in animals, including cell differentiation, the cell cycle, and cell apoptosis. However, their characterization in mollusks is currently lacking.

Results

The current study focused on a comprehensive analysis of the ETS genes in blood clam Tegillarca granosa and other mollusk genomes. Our phylogenetic analysis revealed the absence of the SPI and ETV subfamilies in mollusks compared to humans. Additionally, several ETS genes in mollusks were found to lack the PNT domain, potentially resulting in a diminished ability of ETS proteins to bind target genes. Interestingly, the bivalve ETS1 genes exhibited significantl

SUBMITTER: Jin H 

PROVIDER: S-EPMC10664356 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature