Genome-scale metabolic models reveal determinants of phenotypic differences in non-Saccharomyces yeasts.

ABSTRACT:

Background

Use of alternative non-Saccharomyces yeasts in wine and beer brewing has gained more attention the recent years. This is both due to the desire to obtain a wider variety of flavours in the product and to reduce the final alcohol content. Given the metabolic differences between the yeast species, we wanted to account for some of the differences by using in silico models.

Results

We created and studied genome-scale metabolic models of five different non-Saccharomyces species using an automated processes. These were: Metschnikowia pulcherrima, Lachancea thermotolerans, Hanseniaspora osmophila, Torulaspora delbrueckii and Kluyveromyces lactis. Using the models, we predicted that M. pulcherrima, when compared to the other species, conducts more respiration and thus pro

SUBMITTER: Pettersen JP 

PROVIDER: S-EPMC10664357 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature