Enabling Al sacrificial anodes in tetrahydrofuran electrolytes for reductive electrosynthesis.

ABSTRACT: Al⁰ is widely used as a sacrificial anode in organic electrosynthesis. However, there remains a notable knowledge gap in the understanding of Al anode interface chemistry under electrolysis conditions. We hypothesize that Al interfacial chemistry plays a pivotal role in the discernible bias observed in solvent selections for reductive electrosynthesis. The majority of existing methodologies that employ an Al sacrificial anode use N,N-dimethylformamide (DMF) as the preferred solvent, with only isolated examples of ethereal solvents such as tetrahydrofuran (THF). Given the crucial role of the solvent in determining the efficiency and selectivity of an organic reaction, limitations on solvent choice could significantly hinder substrate reactivity and impede the desire

SUBMITTER: Zhang W 

PROVIDER: S-EPMC10664456 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature