Non-invasive neuromodulation: an emerging intervention for visceral pain in gastrointestinal disorders.

ABSTRACT: Gastrointestinal (GI) disorders, which extend from the esophagus to the anus, are the most common diseases of the GI tract. Among these disorders, pain, encompassing both abdominal and visceral pain, is a predominant feature, affecting the patients' quality of life and imposing a substantial financial burden on society. Pain signals originating from the gut intricately shape brain dynamics. In response, the brain sends appropriate descending signals to respond to pain through neuronal inhibition. However, due to the heterogeneous nature of the disease and its limited pathophysiological understanding, treatment options are minimal and often controversial. Consequently, many patients with GI disorders use complementary and alternative therapies such as neuromodulation to treat visceral pain.

SUBMITTER: Alam MJ 

PROVIDER: S-EPMC10664460 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature