Analysis of codon usage patterns in 48 Aconitum species.

ABSTRACT:

Background

The Aconitum genus is a crucial member of the Ranunculaceae family. There are 350 Aconitum species worldwide, with about 170 species found in China. These species are known for their various pharmacological effects and are commonly used to treat joint pain, cold abdominal pain, and other ailments. Codon usage bias (CUB) analysis contributes to evolutionary relationships and phylogeny. Based on protein-coding sequences (PCGs), we selected 48 species of Aconitum for CUB analysis.

Results

The results revealed that Aconitum species had less than 50% GC content. Furthermore, the distribution of GC content was irregular and followed a trend of GC₁ > GC₂ > GC₃, indicating a bias towards A/T bases. The relative synonymous codon usage (RSCU

SUBMITTER: Yang M 

PROVIDER: S-EPMC10664653 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature