Bifidobacterium infantis as a probiotic in preterm infants: a systematic review and meta-analysis.

ABSTRACT:

Background

Bifidobacterium infantis has special abilities to utilise human milk oligosaccharides. Hence we hypothesised that probiotic supplements containing B. infantis may confer greater benefits to preterm infants than probiotic supplements without B. infantis.

Methods

A systematic review with meta-analysis was conducted according to standard guidelines. We selected RCTs evaluating probiotics compared to placebo or no treatment in preterm and/or low birth weight infants. Probiotic effects on Necrotizing Enterocolitis (NEC), Late Onset Sepsis (LOS) and Mortality were analysed separately for RCTs in which the supplemented probiotic product contained B. infantis and those that did not contain B. infantis.

Results

67 RCTs were included (n = 14,606), of which 16 used pr

SUBMITTER: Batta VK 

PROVIDER: S-EPMC10665187 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature