Reported baseline variables in transsphenoidal surgery for pituitary adenoma over a 30 year period: a systematic review.

ABSTRACT:

Purpose

Heterogeneous reporting in baseline variables in patients undergoing transsphenoidal resection of pituitary adenoma precludes meaningful meta-analysis. We therefore examined trends in reported baseline variables, and degree of heterogeneity of reported variables in 30 years of literature.

Methods

A systematic review of PubMed and Embase was conducted on studies that reported outcomes for transsphenoidal surgery for pituitary adenoma 1990-2021. The protocol was registered a priori and adhered to the PRISMA statement. Full-text studies in English with > 10 patients (prospective), > 500 patients (retrospective), or randomised trials were included.

Results

178 studies were included, comprising 427,659 patients: 52 retrospective (29%); 118 prospective (66%); 9 rand

SUBMITTER: Layard Horsfall H 

PROVIDER: S-EPMC10665258 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature