Safety and efficacy of remimazolam compared with midazolam during bronchoscopy: a single-center, randomized controlled study.

ABSTRACT: Although remimazolam is an ultra-short-acting benzodiazepine with a shorter elimination half-life and faster recovery time than midazolam, studies evaluating its safety and efficacy during bronchoscopy are limited. This study aimed to compare the safety and efficacy of remimazolam with those of midazolam for bronchoscopy. This prospective randomized parallel-group study was conducted at a single institution. The primary outcome was the time from the end of the procedure to full alertness. Other procedural time parameters, satisfaction profiles, and adverse effects were thoroughly evaluated. The time taken to reach peak sedation and the time from the end of the procedure to full alertness was significantly shorter in the remimazolam group than in the midazolam group (median [interquartile r

SUBMITTER: Kim SH 

PROVIDER: S-EPMC10665376 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature