Racial and Ethnic Disparity in Preoperative Chemosensitivity and Survival in Patients With Early-Stage Breast Cancer.

ABSTRACT:

Importance

It remains unclear what survival benefit is associated with preoperative chemosensitivity after receiving neoadjuvant chemotherapy (NACT) among patients with resectable breast cancer from diverse racial and ethnic backgrounds.

Objective

To investigate racial and ethnic disparities in chemosensitivity and association with survival in patients with early-stage breast cancer.

Design, setting, and participants

This retrospective cohort study queried data from the National Cancer Database (NCDB) between calendar years 2010 and 2018. Participants included patients with breast cancer with clinical stage I to III disease treated with NACT. Preoperative chemosensitivity was defined as very sensitive (ypT0N0), sensitive (pathologic TNM stage less than clinical stage,

SUBMITTER: Roy AM 

PROVIDER: S-EPMC10665980 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature