Design of a dual randomized trial in a type 2 hybrid effectiveness-implementation study.

ABSTRACT:

Background

Dual randomized controlled trials (DRCT) are type 2 hybrid studies that include two randomized trials: one testing implementation strategies and one testing an intervention. We argue that this study design offers efficiency by providing rigorous investigation of both implementation and intervention in one study and has potential to accelerate generation of the evidence needed to translate interventions that work into real-world practice. Nevertheless, studies using this design are rare in the literature.

Main text

We construct a paradigm that breaks down the components of the DRCT and provide a step-by-step explanation of features of the design and recommendations for use. A clear distinction is made between the dual strands that test the implementation versus the

SUBMITTER: Stevens J 

PROVIDER: S-EPMC10666326 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature