Molecular epidemiology and characteristics of respiratory syncytial virus among hospitalized children in Guangzhou, China.

ABSTRACT:

Background

Human respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection and hospitalization, especially in children. Highly mutagenic nature and antigenic diversity enable the RSV to successfully survive in human population. We conducted a molecular epidemiological study during 2017-2021 to investigate the prevalence and genetic characteristics of RSV.

Methods

A total of 6499 nasopharyngeal (NP) swabs were collected from hospitalized children at Department of Pediatrics, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, China. All NP swab specimens were preliminary screened for common respiratory viruses and then tested for RSV using specific PCR assays. Partial G genes of RSV were amplified for phyl

SUBMITTER: Umar S 

PROVIDER: S-EPMC10666375 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature