Evaluation of cholesterol transformation abilities and probiotic properties of Bacteroides dorei YGMCC0564.

ABSTRACT: Hypercholesterolemia, a risk factor for cardiovascular disease (CVD), often requires therapeutic agents with varying degrees of side effects. This has created a need for safe and natural alternatives such as medications or functional foods that can improve lipid metabolism and reduce cholesterol levels. In recent years, Next-generation probiotics (NGPs) have recently emerged as a potential solution, offering distinct mechanisms compared to traditional probiotics. Among the NGPs, Bacteroides, a dominant bacterial genus in the human gut, has gained significant attention due to its prevalence, ability to break down plant polysaccharides, and production of short-chain fatty acids (SCFAs). Recent evidence has demonstrated that Bacteroides effectively reduces cholesterol levels, pr

SUBMITTER: He Z 

PROVIDER: S-EPMC10666794 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature