Preoperative versus postoperative misoprostol use for prevention of blood loss during caesarean section in pregnant women at term: a multi-centre randomised controlled trial.

ABSTRACT:

Objective

Caesarean section is associated with higher blood loss than vaginal delivery. This study was performed to compare the safety and efficacy of preoperative versus postoperative rectal and sublingual misoprostol use for prevention of blood loss in women undergoing elective caesarean delivery.

Methods

Eligible patients in Southeast Nigeria were randomly classified into those that received 600 µg of preoperative rectal, postoperative rectal, preoperative sublingual, and postoperative sublingual misoprostol. All patients received 10 units of intravenous oxytocin immediately after delivery. Data were analysed with SPSS Version 23.

Results

Preoperative sublingual misoprostol use caused the highest postoperative packed cell volume, least change in the packed cell vol

SUBMITTER: Ajah LO 

PROVIDER: S-EPMC10666823 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature