Per- and polyfluoroalkyl substances (PFAS) exposure and thyroid cancer risk.

ABSTRACT:

Background

Although per- and polyfluoroalkyl substances (PFAS) exposure is a potential contributor to the increasing thyroid cancer trend, limited studies have investigated the association between PFAS exposure and thyroid cancer in human populations. We therefore investigated associations between plasma PFAS levels and thyroid cancer diagnosis using a nested case-control study of patients with thyroid cancer with plasma samples collected at/before cancer diagnosis.

Methods

88 patients with thyroid cancer using diagnosis codes and 88 healthy (non-cancer) controls pair-matched on sex, age (±5 years), race/ethnicity, body mass index, smoking status, and year of sample collection were identified in the BioMe population (a medical record-linked biobank at the Icahn School of Med

SUBMITTER: van Gerwen M 

PROVIDER: S-EPMC10667111 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature