Theophylline, a drug efficient to increase intracranial pressure. Case report and review of literature.

ABSTRACT:

Introduction

Limited information is available regarding the direct effect of drugs prescribed to elevate intracranial pressure (ICP) in contrast to the abundance of evidence in support of medication utilized to lower ICP. Theophylline is a methylxanthine derivate used in the treatment of respiratory diseases with only a few randomized control trials or case reports describing pain improvement in low CSF pressure states or spontaneous intracranial hypotension (SIH). We present the case of a recorded increase in intracranial pressure under theophylline.

Case report

A 23-year-old female with a complex history of hydrocephalus and syringomyelia was experiencing debilitating symptoms due to refractory intracranial hypotension. Medical management with oral theophylline was attempt

SUBMITTER: Curran A 

PROVIDER: S-EPMC10668101 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature