Prognostic significance of platelet-to-lymphocyte ratio (PLR) in patients with breast cancer treated with neoadjuvant chemotherapy: a meta-analysis.

ABSTRACT:

Objective

Platelet-to-lymphocyte ratio (PLR), known as a key systemic inflammatory parameter, has been proved to be associated with response to neoadjuvant therapy in breast cancer (BC); however, the results remain controversial. This meta-analysis was carried out to evaluate the prognostic values of PLR in patients with BC treated with neoadjuvant chemotherapy (NACT).

Design

Meta-analysis.

Data sources

Relevant literature published on the following databases: PubMed, Embase, Web of Science databases and the Cochrane Library.

Eligibility criteria

All studies involving patients with BC treated with NACT and peripheral blood pretreatment PLR recorded were included.

Data extraction and synthesis

Two researchers independently extracted and evaluated HR/OR an

SUBMITTER: Qi X 

PROVIDER: S-EPMC10668253 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature