Nationwide consensus on the clinical management of treatment-resistant depression in Italy: a Delphi panel.

ABSTRACT:

Background

Treatment-resistant depression (TRD) is defined by the European Medicines Agency as a lack of clinically meaningful improvement after treatment, with at least two different antidepressants. Individual, familiar, and socio-economic burden of TRD is huge. Given the lack of clear guidelines, the large variability of TRD approaches across different countries and the availability of new medications to meet the need of effective and rapid acting therapeutic strategies, it is important to understand the consensus regarding the clinical characteristics and treatment pathways of patients with TRD in Italian routine clinical practice, particularly in view of the recent availability of esketamine nasal spray.

Methods

A Delphi questionnaire with 17 statements (with a 7 points

SUBMITTER: Maina G 

PROVIDER: S-EPMC10668442 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature