Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits.

ABSTRACT: Hair follicle development directly affects the development of the rabbit fur industry. The growth and development of a hair follicle is modified and regulated by many genes and mechanisms. M⁶A is an important RNA modification. However, there are few studies on the effects of the regulation of m⁶A on hair follicle growth and development. In this study, hematoxylin-eosin (HE) staining was used to explore the difference in hair follicle development between Rex rabbits and Hycole rabbits, and we performed m⁶A sequencing to identify the key genes with m⁶A modification in hair follicle growth. The results showed that the hair length, coarse hair percentage, primary hair follicle ratio, and skin thickness of Hycole rabbits were significantly higher than

SUBMITTER: Luo G 

PROVIDER: S-EPMC10669094 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature