Neurofeedback and Affect Regulation Circuitry in Depressed and Healthy Adolescents.

ABSTRACT: Neurodevelopmental psychopathology seeks to understand higher-order emotion regulation circuitry to develop new therapies for adolescents with depression. Depressed (N = 34) and healthy youth (N = 19) completed neurofeedback (NF) training and exhibited increased bilateral amygdala and hippocampus activity in the region of interest (ROI) analyses by recalling positive autobiographical memories. We tested factors supportive of the engagement of emotion regulation's neural areas during NF (i.e., parental support, medication, and gender effects upon anterior cingulate cortex (ACC) engagement). Whole-brain analyses yielded effects of NF vs. control condition and effects of diagnosis. Youth showed higher amygdala and hippocampus (AMYHIPPO) activity during the NF vs. control conditi

SUBMITTER: Nguyen GH 

PROVIDER: S-EPMC10669603 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature