Assessment of dose to vaginal mucosa for gynecologic template interstitial high-dose-rate brachytherapy using Monte Carlo simulation.

ABSTRACT:

Purpose

This study investigated reliable vaginal mucosa dose-volume histogram (DVH) metrics in gynecologic template interstitial high-dose-rate brachytherapy (HDR-BT) for the purpose of standardized dose reporting.

Material and methods

Gynecologic template (Syed/Neblett) interstitial HDR-BT patients treated from September 2016 to November 2022 at the study institute were included in the cohort. Each patient implant included a vaginal mucosa contour defined by a 5 mm expansion from vaginal cylinder, then another volume with clinical target volume subtracted. DVH metrics were investigated between D_0.1cc to D_4cc. Clinical plans were re-calculated using Monte Carlo (MC) simulations both in heterogeneous material and in water.

Results

The patient coho

SUBMITTER: Elburg DV 

PROVIDER: S-EPMC10669914 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature