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Rapid and Accurate Diagnosis of Dermatophyte Infections Using the DendrisCHIP® Technology.


ABSTRACT: Dermatophytosis is a superficial fungal infection with an ever-increasing number of patients. Culture-based mycology remains the most commonly used diagnosis, but it takes around four weeks to identify the causative agent. Therefore, routine clinical laboratories need rapid, high throughput, and accurate species-specific analytical methods for diagnosis and therapeutic management. Based on these requirements, we investigated the feasibility of DendrisCHIP® technology as an innovative molecular diagnostic method for the identification of a subset of 13 pathogens potentially responsible for dermatophytosis infections in clinical samples. This technology is based on DNA microarray, which potentially enables the detection and discrimination of several germs in a single sample. A maj

SUBMITTER: Anton A 

PROVIDER: S-EPMC10670032 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature