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Raman Spectroscopy Spectral Fingerprints of Biomarkers of Traumatic Brain Injury.


ABSTRACT: Traumatic brain injury (TBI) affects millions of people of all ages around the globe. TBI is notoriously hard to diagnose at the point of care, resulting in incorrect patient management, avoidable death and disability, long-term neurodegenerative complications, and increased costs. It is vital to develop timely, alternative diagnostics for TBI to assist triage and clinical decision-making, complementary to current techniques such as neuroimaging and cognitive assessment. These could deliver rapid, quantitative TBI detection, by obtaining information on biochemical changes from patient's biofluids. If available, this would reduce mis-triage, save healthcare providers costs (both over- and under-triage are expensive) and improve outcomes by guiding early management. Herein, we utilize Raman

SUBMITTER: Harris G 

PROVIDER: S-EPMC10670390 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature