Surgical Management of Adult Brainstem Gliomas: A Systematic Review and Meta-Analysis.

ABSTRACT: The present review aims to investigate the survival and functional outcomes in adult high-grade brainstem gliomas (BGSs) by comparing data from resective surgery and biopsy. MEDLINE, EMBASE and Cochrane Library were screened to conduct a systematic review of the literature, according to the PRISMA statement. Analysis was limited to articles including patients older than 18 years of age and those published from 1990 to September 2022. Case reports, review articles, meta-analyses, abstracts, reports of aggregated data, and reports on multimodal therapy where surgery was not the primary treatment were excluded. The ROBINS-I tool was applied to evaluate the risk of bias. Six studies were ultimately considered for the meta-analysis. The resective group was composed of 213 subjects and the biopt

SUBMITTER: Ius T 

PROVIDER: S-EPMC10670486 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature