Early Life Factors and Polycystic Ovary Syndrome in a Swedish Birth Cohort.

ABSTRACT: Polycystic ovary syndrome (PCOS) is a medical condition with important consequences for women's well-being and reproductive outcomes. Although the etiology of PCOS is not fully understood, there is increasing evidence of both genetic and environmental determinants, including development in early life. We studied a population of 977,637 singleton women born in in Sweden between 1973 and 1995, followed sometime between the age 15 and 40. The incidence of PCOS was measured using hospital register data during 2001-2012, complemented with information about the women's, parents' and sisters' health and social characteristics from population and health care registers. Cox regression was used to study how PCOS is associated with intergenerational factors, and a range of early life characteristics.

SUBMITTER: Boldis BV 

PROVIDER: S-EPMC10671095 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature