Selective Sweeps in Cattle Genomes in Response to the Influence of Urbanization and Environmental Contamination.

ABSTRACT: A genomic study was conducted to identify the effects of urbanization and environmental contaminants with heavy metals on selection footprints in dairy cattle populations reared in the megacity of Bengaluru, South India. Dairy cattle reared along the rural-urban interface of Bengaluru with/without access to roughage from public lakeshores were selected. The genotyped animals were subjected to the cross-population-extended haplotype homozygosity (XP-EHH) methodology to infer selection sweeps caused by urbanization (rural, mixed, and urban) and environmental contamination with cadmium and lead. We postulated that social-ecological challenges contribute to mechanisms of natural selection. A number of selection sweeps were identified when comparing the genomes of cattle located in rural, mixed

SUBMITTER: Velayudhan SM 

PROVIDER: S-EPMC10671461 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature