Deep Brain Stimulation for the Management of Refractory Neurological Disorders: A Comprehensive Review.

ABSTRACT: In recent decades, deep brain stimulation (DBS) has been extensively studied due to its reversibility and significantly fewer side effects. DBS is mainly a symptomatic therapy, but the stimulation of subcortical areas by DBS is believed to affect the cytoarchitecture of the brain, leading to adaptability and neurogenesis. The neurological disorders most commonly studied with DBS were Parkinson's disease, essential tremor, obsessive-compulsive disorder, and major depressive disorder. The most precise approach to evaluating the location of the leads still relies on the stimulus-induced side effects reported by the patients. Moreover, the adequate voltage and DBS current field could correlate with the patient's symptoms. Implantable pulse generators are the main parts of the DBS, and their ma

SUBMITTER: Rissardo JP 

PROVIDER: S-EPMC10673515 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature