Telomere-to-telomere assembly of cassava genome reveals the evolution of cassava and divergence of allelic expression.

ABSTRACT: Cassava is a crucial crop that makes a significant contribution to ensuring human food security. However, high-quality telomere-to-telomere cassava genomes have not been available up to now, which has restricted the progress of haploid molecular breeding for cassava. In this study, we constructed two nearly complete haploid resolved genomes and an integrated, telomere-to-telomere gap-free reference genome of an excellent cassava variety, 'Xinxuan 048', thereby providing a new high-quality genomic resource. Furthermore, the evolutionary history of several species within the Euphorbiaceae family was revealed. Through comparative analysis of haploid genomes, it was found that two haploid genomes had extensive differences in linear structure, transcriptome features, and epigenetic characterist

SUBMITTER: Xu XD 

PROVIDER: S-EPMC10673656 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature