A Meta-analysis of Surgical Outcomes of T4a and Infranotch T4b Oral Cancers.

ABSTRACT:

Objective

To determine the overall surgical outcomes of infranotch T4b oral cancers and compare them with T4a oral cancers.

Methods

PubMed, EMBASE and Cochrane databases from 2000 to 2022 were systematically searched. Clinical studies reporting at least one outcome following curative surgery and adjuvant therapy for comparison of patients with either infranotch T4b (IN-T4b) or T4a tumour. The heterogeneity of the included studies was determined using Tau-squared, Chi-squared, and the Higgins I² test. The random effects model was used to determine the log odds ratio (logOR).

Results

The systematic review comprised 11,790 patients from 16 included studies. Seven studies were included in the meta-analysis (n = 11,381). For IN-T4b patients, the pooled 2 and 5 y

SUBMITTER: Rao KN 

PROVIDER: S-EPMC10673764 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature