Semi-continuous dielectrophoretic separation at high throughput using printed circuit boards.

ABSTRACT: Particle separation is an essential part of many processes. One mechanism to separate particles according to size, shape, or material properties is dielectrophoresis (DEP). DEP arises when a polarizable particle is immersed in an inhomogeneous electric field. DEP can attract microparticles toward the local field maxima or repulse them from these locations. In biotechnology and microfluidic devices, this is a well-described and established method to separate (bio-)particles. Increasing the throughput of DEP separators while maintaining their selectivity is a field of current research. In this study, we investigate two approaches to increase the overall throughput of an electrode-based DEP separator that uses selective trapping of particles. We studied how particle concentration affects the

SUBMITTER: Giesler J 

PROVIDER: S-EPMC10673871 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature