Preclinical Models of Laryngeal Papillomavirus Infection: A Scoping Review.

ABSTRACT:

Objective

Laryngeal human papillomavirus (HPV) infection causes recurrent respiratory papillomatosis (RRP) and accounts for up to 25% of laryngeal cancers. Lack of satisfactory preclinical models is one reason that treatments for these diseases are limited. We sought to assess the literature describing preclinical models of laryngeal papillomavirus infection.

Data sources

PubMed, Web of Science, and Scopus were searched from the inception of database through October 2022.

Review methods

Studies searched were screened by two investigators. Eligible studies were peer-reviewed, published in English, presented original data, and described attempted models of laryngeal papillomavirus infection. Data examined included type of papillomavirus, infection model, and results inc

SUBMITTER: King RE 

PROVIDER: S-EPMC10674042 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature