Template-Free Manufacturing of Defined Structure and Size Polymeric Microparticles.

ABSTRACT: Complex-structured polymeric microparticles hold significant promise as an advance in next-generation medicine mostly due to demand from developing targeted drug delivery. However, the conventional methods for producing these microparticles of defined size, shape, and sophisticated composition often face challenges in scalability, reliance on specialized components such as micro-patterned templates, or limited control over particle size distribution and cargo (functional payload) release kinetics. In this study, we introduce a novel and reliably scalable approach for manufacturing microparticles of defined structures and sizes with variable parameters. The concept behind this method involves the deposition of a specific number of polymer layers on a substrate with low surface energy. Each

SUBMITTER: Abdurashitov AS 

PROVIDER: S-EPMC10674349 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature