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Daphnia magna Multigeneration Exposure to Carbendazim: Gene Transcription Responses.


ABSTRACT: The world population is experiencing colossal growth and thus demand for food, leading to an increase in the use of pesticides. Persistent pesticide contamination, such as carbendazim, remains a pressing environmental concern, with potentially long-term impacts on aquatic ecosystems. In the present study, Daphnia magna was exposed to carbendazim (5 µg L-1) for 12 generations, with the aim of assessing gene transcription alterations induced by carbendazim (using a D. magna custom microarray). The results showed that carbendazim caused changes in genes involved in the response to stress, DNA replication/repair, neurotransmission, ATP production, and lipid and carbohydrate metabolism at concentrations already found in the environment. These outcomes support the result

SUBMITTER: Silva ARR 

PROVIDER: S-EPMC10674461 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature