Three-Dimensional Printer-Assisted Electrospinning for Fabricating Intricate Biological Tissue Mimics.

ABSTRACT: Although regenerative medicine necessitates advanced three-dimensional (3D) scaffolds for organ and tissue applications, creating intricate structures across scales, from nano- to meso-like biological tissues, remains a challenge. Electrospinning of nanofibers offers promise due to its capacity to craft not only the dimensions and surfaces of individual fibers but also intricate attributes, such as anisotropy and porosity, across various materials. In this study, we used a 3D printer to design a mold with polylactic acid for gel modeling. This gel template, which was mounted on a metal wire, facilitated microfiber electrospinning. After spinning, these structures were treated with EDTA to remove the template and were then cleansed and dried, resulting in 3D microfibrous (3DMF) structures,

SUBMITTER: Raje K 

PROVIDER: S-EPMC10675084 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature