Escitalopram versus other antidepressive agents for major depressive disorder: a systematic review and meta-analysis.

ABSTRACT:

Background

Escitalopram is selective serotonin reuptake inhibitors (SSRIs) and one of the most commonly prescribed newer antidepressants (ADs) worldwide. We aimed to explore the efficacy, acceptability and tolerability of escitalopram in comparison with other ADs in the acute-phase treatment of major depressive disorder (MDD).

Methods

Medline/PubMed, EMBASE, the Cochrane Library, CINAHL, and Clinical Trials.gov were searched from inception to July 10, 2023. Trial databases of drug-approving agencies were hand-searched for published, unpublished and ongoing controlled trials. All randomized controlled trials comparing escitalopram against any other antidepressant for patients with MDD. Responders and remitters to treatment were calculated on an intention-to-treat basis. For d

SUBMITTER: Yin J 

PROVIDER: S-EPMC10675869 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature