Immune thrombocytopenic purpura after influenza vaccine administration; a systematic review and meta-analysis.

ABSTRACT:

Background

The American Society of Haematology defines immune thrombocytopenic purpura (ITP) as a common hematologic disorder characterized by a transient or long-term decrease in platelet counts (< 100 × 109/L.), purpura, and haemorrhagic episodes caused by antiplatelet autoantibodies, with the exclusion of other clinical conditions. We aimed to systematically determine the incidence of ITP in adults and children following influenza vaccination, the duration between vaccination and the occurrence of ITP, and to identify predictors of ITP after the vaccine.

Methods

We searched PubMed, Cochrane Library, Google Scholar, Web of Science, Scopus, and Science Direct. We included primary studies that assessed the occurrence of immune thrombocytopenia in individuals who had received

SUBMITTER: Elsaid M 

PROVIDER: S-EPMC10675976 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature