Interaction effects of significant risk factors on low bone mineral density in ankylosing spondylitis.

ABSTRACT:

Background

To analyze individually and interactively critical risk factors, which are closely related to low bone mineral density (BMD) in patient with ankylosing spondylitis (AS).

Methods

A total of 249 AS patients who visited China-Japan Friendship Hospital were included in this training set. Patients with questionnaire data, blood samples, X-rays, and BMD were collected. Logistic regression analysis was employed to identify key risk factors for low BMD in different sites, and predictive accuracy was improved by incorporating the selected significant risk factors into the baseline model, which was then validated using a validation set. The interaction between risk factors was analyzed, and predictive nomograms for low BMD in different sites were established.

Results

SUBMITTER: Sun W 

PROVIDER: S-EPMC10676083 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature