Green synthesis of nano-based drug delivery systems developed for hepatocellular carcinoma treatment: a review.

ABSTRACT: This review presents an overview of one of the effective strategies for improving the anticancer impact of many drugs including sorafenib using a drug delivery system by employing nanoparticles that is produced through a biological system. The biological process has a lot of benefits, including being inexpensive and safe for the environment. Sorafenib is one of a multi-kinase inhibitor that inhibits molecularly targeted kinases. Because of its poor pharmacokinetic characteristics, such as fast elimination and limited water solubility, the bioavailability of Sorafenib is extremely low. More intelligent nano formulations of sorafenib have been developed to boost both the drug's target ability and bioavailability. Researchers in a wide variety of sectors, including nanomedicine, have recently

SUBMITTER: Khafaga DSR 

PROVIDER: S-EPMC10676320 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature