RecView: an interactive R application for locating recombination positions using pedigree data.

ABSTRACT:

Background

Recombination reshuffles alleles at linked loci, allowing genes to evolve independently and consequently enhancing the efficiency of selection. This makes quantifying recombination along chromosomes an important goal for understanding how selection and drift are acting on genes and chromosomes.

Results

We present RecView, an interactive R application and its homonymous R package, to facilitate locating recombination positions along chromosomes or scaffolds using whole-genome genotype data of a three-generation pedigree. RecView analyses and plots the grandparent-of-origin of all informative alleles along each chromosome of the offspring in the pedigree, and infers recombination positions with either of two built-in algorithms: one based on change in the proportion

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10676570 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature