Complications and Treatment of Early-Onset Type 2 Diabetes.

ABSTRACT:

Context

Global reports have revealed a dramatic rise in the number of patients diagnosed with type 2 diabetes (T2DM) over the past three decades in all age groups, even in children and adolescents. The physiologic phenomenon of insulin resistance during puberty, as well as genetic and epigenetic factors, are implicated in this phenomenon. It seems that patients with early-onset T2DM experience a more aggressive clinical course; however, limited treatments available for these patients pose a challenge. This narrative review intends to scrutinize the micro- and macrovascular complications and treatments of patients with early-onset T2DM.

Methods

The literature search was conducted in the PubMed database to identify all relevant original English articles published from the begi

SUBMITTER: Soheilipour F 

PROVIDER: S-EPMC10676662 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature