Multidrug-resistant <i>Escherichia coli</i> isolated from patients and surrounding hospital environments in Bangladesh: A molecular approach for the determination of pathogenicity and resistance.

ABSTRACT: Extended spectrum β-lactamase producing Escherichia coli (ESBL E. coli) is a primary concern for hospital and community healthcare settings, often linked to an increased incidence of nosocomial infections. This study investigated the characteristics of ESBL E. coli isolated from hospital environments and clinical samples. In total, 117 ESBL E. coli isolates were obtained. The isolates were subjected to molecular analysis for the presence of resistance and virulence genes, antibiotic susceptibility testing, quantitative adherence assay, ERIC-PCR for phylogenetic analysis and whole genome sequencing of four highly drug resistant isolates. Out of the 117 isolates, 68.4% were positive for bla_CTX-M, 39.3% for bla_TEM, 30.8% for b

SUBMITTER: Moniruzzaman M 

PROVIDER: S-EPMC10679508 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature