Clinical and microbiological evaluation of ventilator-associated pneumonia in an intensive care unit in Vietnam.

ABSTRACT:

Background

The increasing incidence of multidrug-resistant Gram-negative bacteria causing ventilator-associated pneumonia (VAP) is a global concern. A better understanding of the epidemiology of VAP in Southeast Asia is essential to optimise treatments and patient outcomes.

Methods

VAP epidemiology in an intensive care unit in Vietnam was investigated. A prospective cohort study was conducted. Patients who were ventilated for >48 hours, diagnosed with VAP, and had a positive respiratory culture between October 2015 and March 2017 were included. Whole-genome sequencing (WGS) was performed on Acinetobacter baumannii isolates.

Results

We identified 125 patients (137 episodes) with VAP from 1,699 admissions. Twelve patients had 2 VAP episodes. The median age was 60

SUBMITTER: Hayakawa K 

PROVIDER: S-EPMC10679888 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature