Genetic mapping identifies SNP mutations in MITF-M promoter associated with melanin formation in Putian black duck.

ABSTRACT: The coloration of plumage in poultry species has substantial economic significance. Putian black ducks encompass 2 distinct strains characterized by black and white plumage variations resulting from selective breeding. This study aimed to identify the molecular mechanisms responsible for plumage coloration in these 2 distinct strains. A comprehensive genome-wide association study was conducted using DNA data sourced from a F2 segregating population, consisting of 71 individuals with black plumage and 39 individuals with white plumage, derived from these distinct 2 strains. This analysis revealed that 894 nucleotide polymorphisms and identified 58 candidate genes. Subsequent Gene Ontology and Kyoto Encyclopedia of Genes and Genomes coenrichment analyses identified MITF as a key candidate ge

SUBMITTER: Lin R 

PROVIDER: S-EPMC10679944 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature