A new ferroptosis-related signature model including messenger RNAs and long non-coding RNAs predicts the prognosis of gastric cancer patients.

ABSTRACT:

Background and objectives

Gastric cancer (GC) is among the most malignant tumor types, which causes heavy healthy and economic burden to the people and societies all around the world. Establishment of an effective set of prognostic marker will benefit a lot to the treatment of GC patients clinically. Ferroptosis is a newly identified regulated cell death modality, with tight relevance with GC development. However, its application in the prognosis of GC has not been studied in detail. Deregulated messenger RNA (mRNA) and long non-coding RNA (lncRNA) expression profile in tumor can serve as novel prognostic marker for predicting the survival and cancer relapse in patients.

Methods

We downloaded ferroptosis-related gene expression microarray data, clinicopathologic information

SUBMITTER: Liu Y 

PROVIDER: S-EPMC10680379 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature