Optomechanical assessment of photorefractive corneal cross-linking via optical coherence elastography.

ABSTRACT: Purpose: Corneal cross-linking (CXL) has recently been used with promising results to positively affect corneal refractive power in the treatment of hyperopia and mild myopia. However, understanding and predicting the optomechanical changes induced by this procedure are challenging. Methods: We applied ambient pressure modulation based optical coherence elastography (OCE) to quantify the refractive and mechanical effects of patterned CXL and their relationship to energy delivered during the treatment on porcine corneas. Three different patterned treatments were performed, designed according to Zernike polynomial functions (circle, astigmatism, coma). In addition, three different irradiation protocols were analyzed: standard Dresden CXL (fluence of 5.4 J/c

SUBMITTER: Frigelli M 

PROVIDER: S-EPMC10680454 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature