An Unusual Case of Delayed Midazolam Anaphylaxis and a Review of the Current Literature.

ABSTRACT: Midazolam is a commonly used, well-tolerated, anxiolytic, sedative, anesthesia induction agent, and an adjunct for procedural sedation that is used widely in the emergency department. The ability to administer midazolam via multiple routes, including intranasal, makes it a particularly common choice for use in children. Intranasal administration is safe, easy, and well tolerated and has been shown to be an effective method of obtaining anxiolysis and/or sedation. Adverse drug reactions, including allergic reactions, can occur with any medication. However, anaphylaxis is an uncommon phenomenon from midazolam. Despite being one of the most common medications used in the emergency department and operating room, there are only a handful of unequivocal cases of anaphylaxis secondary to midazola

SUBMITTER: Cochran-Caggiano NC 

PROVIDER: S-EPMC10681077 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature