Role of ultra-high b-value DWI in the imaging of hereditary leiomyomatosis and renal cell carcinoma (HLRCC).

ABSTRACT:

Purpose

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome is associated with an aggressive form of renal cell carcinoma with high risk of metastasis, even in small primary tumors with unequivocal imaging findings. In this study, we compare the performance of ultra-high b-value diffusion-weighted imaging (DWI) sequence (b = 2000 s/mm²) to standard DWI (b = 800 s/mm²) sequence in identifying malignant lesions in patients with HLRCC.

Methods

Twenty-eight patients (n = 18 HLRCC patients with 22 lesions, n = 10 controls) were independently evaluated by three abdominal radiologists with different levels of experience using four combinations of MRI sequences in two separate sessions (session 1: DWI with b-800, session 2: DWI with b-2000). T1

SUBMITTER: Chaurasia A 

PROVIDER: S-EPMC10681094 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature