Delivery of a novel intervention to facilitate liberation from mechanical ventilation in paediatric intensive care: A process evaluation.

ABSTRACT:

Background

Prolonged mechanical ventilation increases the risk of mortality and morbidity. Optimising sedation and early testing for possible liberation from invasive mechanical ventilation (IMV) has been shown to reduce time on the ventilator. Alongside a multicentre trial of sedation and ventilation weaning, we conducted a mixed method process evaluation to understand how the intervention content and delivery was linked to trial outcomes.

Methods

10,495 children admitted to 18 paediatric intensive care units (ICUs) in the United Kingdom participated in a stepped-wedge, cluster randomised controlled trial, with 1955 clinical staff trained to deliver the intervention. The intervention comprised assessment and optimisation of sedation levels, and bedside screening of respirat

SUBMITTER: Jordan J 

PROVIDER: S-EPMC10681213 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature