The frequency of complications in a cohort of patients diagnosed with hemophilia A and hemophilia B receiving prophylactic treatment in Colombia: A retrospective noninterventional study.

ABSTRACT:

Introduction

Hemophilia A and B are disorders associated with the deficit of coagulation factors VIII and IX.

Objective

Was to determine the incidence of complications in a cohort of patients diagnosed with moderate and severe hemophilia A or B under treatment in a specialized institution.

Methods

A retrospective study of a cohort of patients with replacement therapy for hemophilia A or B, evaluating treatment and complications between January/2012 and July/2019. Sociodemographic, clinical and disease management-related variables were extracted from the medical records. Time to inhibitor development and rate associated with bleeding and hospitalizations were evaluated.

Results

A total of 159 male patients were identified with hemophilia A (n = 140; 88.1%) and B

SUBMITTER: Machado Alba JE 

PROVIDER: S-EPMC10681305 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature