Targeted Mass Azithromycin Distribution for Trachoma: A Community-Randomized Trial (TANA II).

ABSTRACT:

Background

Current guidelines recommend annual community-wide mass administration of azithromycin for trachoma. Targeting treatments to those most likely to be infected could reduce the amount of unnecessary antibiotics distributed.

Methods

In a cluster-randomized trial conducted from 1 November 2010 through 8 November 2013, 48 Ethiopian communities previously treated with annual mass azithromycin distributions for trachoma were randomized in equal numbers to (1) annual azithromycin distributions targeted to children aged 0-5 years, (2) annual azithromycin distributions targeted to households with a child aged 0-5 years found to have clinically active trachoma, (3) continued annual mass azithromycin distributions to the entire community, or (4) cessation of treatment. The pr

SUBMITTER: Mahmud H 

PROVIDER: S-EPMC10681647 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature